FRUZAQLA™ (fruquintinib)     A new, once-daily non-chemotherapy oral treatment for previously treated metastatic colorectal cancer (mCRC)      

FRUZAQLA is an innovative treatment for adults with colorectal cancer (CRC) that has spread to other parts of the body. It is used by people who have received previous treatment with certain anti-cancer medicines.

Now approved.

What is FRUZAQLA and how does it work?

FRUZAQLA (FRU-ZAHK-LA) works by starving tumors of nutrients and oxygen, which can stop tumor growth. It was designed to block proteins called vascular endothelial growth factor receptors (VEGFR). By blocking VEGFR, FRUZAQLA blocks blood supply from feeding the tumor.

1st icon.

FRUZAQLA is the first targeted therapy for mCRC approved in nearly a decade

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The efficacy and safety of FRUZAQLA versus placebo was studied across 2 clinical trials, which included more than 1,100 people whose mCRC had been previously treated

7.4 months.

In one of these clinical trials, people taking FRUZAQLA lived longer (7.4 months) compared to those taking placebo, a sugar pill (4.8 months)

1 pill once daily.

FRUZAQLA is an oral kinase inhibitor capsule taken at home with or without food. The recommended dose of FRUZAQLA is 5 mg once daily for the first 21 days followed by 7 days off treatment for each 28-day cycle.

What are the possible side effects of FRUZAQLA? 

The most common side effects in people treated with FRUZAQLA included:

  • Voice changes or hoarseness
  • Stomach-area (abdominal) pain
  • Diarrhea
  • Weakness, lack of strength and energy, and feeling very tired or sleepy (asthenia)

These are not all the possible side effects of FRUZAQLA.

  • 38% of people treated with FRUZAQLA had serious side effects 
  • The most common serious side effects were severe bleeding (hemorrhage) and a tear in your stomach or intestinal wall (gastrointestinal perforation)

The most common side effects went away within 3 weeks. Your doctor can help you manage your side effects while taking FRUZAQLA.

Talk to your doctor today and see if FRUZAQLA is right for you.

Talking with your doctor about your mCRC isn’t always easy, but arriving prepared with questions at your next visit may help you get the information you’re looking for. Consider using these questions to start the conversation:

  1. Can you help me understand how FRUZAQLA works?
  2. Could FRUZAQLA be right for someone like me?
  3. How often will my FRUZAQLA treatment be monitored?
  4. What are possible side effects of FRUZAQLA, and what should I do if I experience any?
  5. How do I take FRUZAQLA, and what is the dosing schedule?
  6. How often will I need to come into the office while taking FRUZAQLA?
  7. How will taking FRUZAQLA affect my ability to continue my daily activities?
  8. Does Takeda Oncology offer patient support or financial assistance programs?

We’re here to help support you

From helping you understand coverage options to identifying available financial assistance, Takeda Oncology Here2Assist is committed to offering you comprehensive support throughout your treatment.

Support organizations for you and your caregivers

There are many resources available to you, whether you are new to FRUZAQLA treatment or are looking for more information so you can talk with your healthcare provider about it.

Besides the support you receive from your oncology team, there may be additional supportive resources available. You can become an even more active participant in your care by reaching out and finding the people, tools, and educational resources that you need for support.

Takeda Oncology is not affiliated with any of these organizations. By listing these resources, Takeda Oncology is not endorsing any particular service or group and we are not responsible for the content of these sites or services. They are provided here for informational purposes and are not meant to replace your healthcare provider’s medical advice.


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